Table 1.

Description of 11 polymorphic markers studied in the CYP2E1 gene.

Marker	Function	Polymorphism	dbSNP rs#	Site Location	Positiond (bp)	Base pairs to next SNP	ALFRED UIDa	ADeles	Ancestral allele
1	none proven	VNTR		5′ upstream	135,188,828	885b	SI01 40900	4 alleles	NAc
2		C_2431875_10;Pstl	rs3813867	5′ upstream	135,189,595	240	SI000693S	G/G	G
3		Rsal	rs2031920	5′ upstream	135,189,835	703	S1000694T	C/T	C
4		C_15867697_1D	rs2070672	5′ upstream	135,190,538	281	SI001473P	G/A	A
5		C_25594209_10	rs641342Q	5′ upstream	135,190,819	4,846	SI001475R	T/G	G
6	Val179lle	C_30443971_10	rs6413419	exon 4	135,195,665	1,722	SI001468T	G/A	G
7	lle321lle	C_7468401_10	rs915909	exon 6	135,197,387	330	SI001476S	T/C	C
8		C_30173803_10; Mspl	rs4646976	intron 6	135,197,717	817	SI000692R	A/G	A
9		Dral	rs6413432	intron 6	135,198,534	2,593	SI014089W SI014088V	A/T	A
10		C_16026001_20	rs2070676	intron 7	135,201,127	225		GIC	G
11	Phe421Phe	C_16026002_10	rs2515641	exon 8	135,201,352		SI000174Q	TC	C

VNTR has two common (6-, 8-repeats described by Hu el al.1999) alleles; two rare alleles observed in African samples.

^a“UIDs” are unique identifiers in the ALFRED database for polymorphism descriptions and allele frequencies.

^bDistance to next SNP (bp) from the proximal end of the VNTR

^cNot Available; Failed to identify ancestral allele for VNTR

^dNCBI Map Build 36.3