Skip to main content
. Author manuscript; available in PMC: 2010 Sep 1.
Published in final edited form as: Neurobiol Aging. 2007 Dec 21;30(9):1350–1360. doi: 10.1016/j.neurobiolaging.2007.11.014

Figure 3.

Figure 3

Cytokine production in APOE4/4 microglia compared to APOE3/3 microglia. Supernatant levels of TNFα (A); IL-6 (B); IL-12 p40 (C) and IL-4 (D) were measured after 24 hrs of treatment with LPS (100 ng/ml) + IFNγ (100 U/ml). Significantly increased levels for APOE4/4 microglia compared to APOE3/3 microglia were observed for TNFα, IL-6 and IL-12 while a significant decrease was observed for IL-4 (* = p < 0.001; unpaired student’s t test).