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. Author manuscript; available in PMC: 2009 Nov 25.
Published in final edited form as: Immunity. 2008 Apr;28(4):477–487. doi: 10.1016/j.immuni.2008.03.002

Figure 2. G-CSFR signaling.

Figure 2

Simplified schematic of G-CSFR signaling to illustrate that Stat3 and Stat5 are regulated by the G-CSFR and that Socs3 is a key downstream target of Stat3. Socs3 is required to feedback inhibit G-CSFR signaling.