. Author manuscript; available in PMC: 2009 Nov 25.

Published in final edited form as: Pediatrics. 2008 Jun 2;122(1):e129–e138. doi: 10.1542/peds.2007-2467

TABLE 4.

Association of Entry z Scores With Measures of Disease Status and Previous ART in P1010 Population

Metabolite (n)	CD4% (Per 10% Higher)		HIV RNA (Per 1 log₁₀ Copies per mL Higher)		CDC Category (vs Category A/N)				Previous ART (vs ART Naive)

	Adjusted z Score Difference (95% CI) at Entry	P	Adjusted z Score Difference (95% CI) at Entry	P	Category B		Category C		PI Exposed		PI Naive
	Adjusted z Score Difference (95% CI) at Entry	P	Adjusted z Score Difference (95% CI) at Entry	P	Adjusted z Score Difference (95% CI) at Entry	P	Adjusted z Score Difference (95% CI) at Entry	P	Adjusted z Score Difference (95% CI) at Entry	P	Adjusted z Score Difference (95% CI) at Entry	P
	HDL cholesterol (n=65)	0.28 (0.00 to 0.56)	.053	−0.26 (−0.72 to 0.20)	.260	−0.19 (−0.96 to 0.59)	.630	−0.14 (−1.05 to 0.77)	.760	−0.23 (−1.11 to 0.66)	.610	−0.69 (−1.73 to 0.35)	.190
LDL cholesterol (n=66)	0.18 (−0.19 to 0.54)	.340	0.15 (−0.47 to 0.77)	.630	−0.21 (−1.22 to 0.80)	.680	−1.78 (−2.96 to−0.60)	.004^a	0.76 (−0.39 to 1.91)	.190	0.14 (−1.20 to 1.49)	.830
Total cholesterol (n=65)	0.01 (−0.22 to 0.41)	.550	−0.01 (−0.52 to 0.50)	.970	−0.16 (−1.03 to 0.70)	.700	−1.20 (−2.21 to−0.18)	.022^a	1.05 (0.06 to 2.04)	.039^a	0.34 (−0.81 to 1.50)	.550
Total-HDL cholesterol ratio	−0.21 (−0.53 to 0.10)	.190	0.22 (−0.29 to 0.72)	.400	0.13 (−0.73 to 1.00)	.750	−0.59 (−1.59 to 0.42)	.250	0.96 (−0.02 to 1.94)	.056	1.01 (−0.14 to 2.16)	.084
(n=65)
Triglycerides (n=65)	−0.22 (−0.55 to 0.12)	.200	−0.067 (−0.60 to 0.47)	.800	0.27 (−0.64 to 1.18)	.560	0.85 (−0.22 to 1.92)	.120	0.43 (−0.61 to 1.48)	.410	0.08 (−1.14 to 1.29)	.900
Apolipoprotein A1 (n=50)	0.11 (−0.29 to 0.50)	.590	−0.43 (−1.05 to 0.19)	.170	−0.10 (−1.12 to 0.92)	.850	0.02 (−1.18 to 1.22)	.970	0.50 (−0.64 to 1.63)	.380	−0.17 (−1.58 to 1.24)	.810
Apolipoprotein B (n=50)	−0.15 (−0.61 to 0.31)	.510	−0.12 (−0.84 to 0.59)	.730	0.26 (−0.91 to 1.44)	.660	−0.76 (−2.14 to 0.62)	.270	1.10 (−0.21 to 2.41)	.097	0.36 (−1.26 to 1.98)	.650

Results are from multivariate models that were adjusted for all variables in table and dietary intake in excess of recommended cholesterol and total fat; there were no significant associations with glucose, insulin, or HOMA-IR n is the number of observations included in the analyses.

Significant (P<.05).