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. 1999 Apr 10;318(7189):978–979. doi: 10.1136/bmj.318.7189.978

Table.

Responses to the survey questions testing knowledge of paracetamol toxicity 1 week and 32 weeks after broadcast of an episode of Casualty depicting a paracetamol overdose: comparison of the knowledge of those who did and did not see the episode. Values are numbers (percentages) of those who responded to question unless stated otherwise

Question and responses Responses 1 week after broadcast
Responses 32 weeks after broadcast
Viewers (n=1030) Non-viewers (n=1762) Odds ratio (95% CI) for viewers v non-viewers; P value
Viewers (n=475) Non-viewers (n=807) Odds ratio (95% CI) for viewers v non-viewers; P value
Crude (n=2792) Adjusted* (n=1168) Crude (n=1282) Adjusted* (n=1168)
Delayed effects of paracetamol
Question: An overdose of one of the following drugs will make a person unwell to start with, then they may feel better, but a few days later they may die from liver damage. Can you say which drug has this effect? Answers: antibiotics, aspirin, Brufen, paracetamol, sleeping tablets, tranquillisers, don’t know
Correct (paracetamol) 877 (85) 786 (45) OR for giving correct answer 361 (76) 392 (49) OR for giving correct answer
Incorrect (other drug) 61 (6) 275 (16) 5.03 (3.75 to 6.75); P<0.0005 4.79 (2.63 to 8.71); P<0.0005 40 (8) 113 (14) 2.60 (1.77 to 3.83); P<0.0005 2.32 (1.42 to 3.81); P=0.001
Don’t know or no answer 92 (9) 701 (40)  74 (16) 302 (37)
Delay in presentation§
Question: What is the latest response time after an overdose of this drug that a person can seek help to avoid this fatal effect? Answers: 6, 12, 24, 48 or 72 hours, or don’t know
6 hours 305 (35) 292 (37) 138 (38) 133 (34)
12 hours 172 (20) 159 (20) OR for reporting shorter times  89 (25)  91 (23) OR for reporting shorter times
24 hours 121 (14) 59 (8) 0.67 (0.54 to 0.83); P<0.0005 0.62 (0.40 to 0.94); P=0.02  43 (12)  41 (10) 0.84 (0.62 to 1.14); P=0.3 0.69 (0.45 to 1.05); P=0.08
48 hours 55 (6) 26 (3) 20 (6)  5 (1)
72 hours 13 (1) 10 (1)  5 (1)  3 (1)
Don’t know or no answer 211 (24) 240 (31)  66 (18) 119 (30)
Fatal dose of paracetamol
Question: What number of tablets of paracetamol do you think could kill a person? Answers: 15, 30, 50, or 100 tablets, or don’t know
15 258 (25) 369 (21) 140 (29) 214 (27)
30 233 (23) 365 (21) OR for reporting lower doses 120 (25) 171 (21) OR for reporting lower doses
50 276 (27) 247 (14) 0.91 (0.77 to 1.06); P=0.2 0.80 (0.57 to 1.11); P=0.18  72 (15) 100 (12) 0.94 (0.74 to 1.21); P=0.6 0.75 (0.53 to 1.04); P=0.09
100 67 (7) 144 (8) 29 (6) 43 (5)
Don’t know or no answer 196 (19) 637 (36) 114 (24) 279 (35)
Comparative toxicity of paracetamol
Question: What number of tablets of each of the following drugs do you think could kill a person? Antibiotics, aspirin, Brufen, paracetamol, sleeping tablets, tranquillisers. Answers: For each drug dose stated as 15, 30, 50 or 100 tablets, or don’t know. Drugs then ranked according to responses
Paracetamol singly most toxic 145 (14) 177 (10) OR for ranking paracetamol as more toxic  88 (19)  82 (10) OR for ranking paracetamol as more toxic
Paracetamol jointly most toxic 570 (55) 796 (45) 1.04 (0.86 to 1.26); P=0.7 0.92 (0.63 to 1.35); P=0.7 236 (50) 399 (49) 1.40 (1.04 to 1.87); P=0.03 1.16 (0.79 to 1.71); P=0.4
Other drug more toxic 119 (12) 152 (9) 37 (8) 47 (6)
Don’t know or no answer 196 (19) 637 (36) 114 (24) 279 (35)
*

Adjusted for age, sex, social class, region, medical viewing habits, self reported medical interest, and general medical knowledge assessed by responses to two test questions. 

Odds ratios (OR) estimated from logistic regression analyses for dichotomous outcomes. 

For all questions, viewers were significantly less likely (P<0.001) not to respond or to respond “don’t know” than non-viewers. These responses were excluded from further analyses. 

§

Only participants who correctly identified paracetamol as the drug causing liver damage are included in this analysis. 

Odds ratios (OR) estimated from proportional odds models for ordinal outcomes, comparing the odds of viewers and non-viewers responding with more appropriate responses of any degree.