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. Author manuscript; available in PMC: 2010 Nov 1.
Published in final edited form as: Hypertension. 2009 Sep 21;54(5):1077–1083. doi: 10.1161/HYPERTENSIONAHA.109.137174

Figure 2.

Figure 2

DOCA/HS-induced renal but not systemic elevations of oxidative stress were attenuated in COMT −/− mice. A: DOCA/HS increased urinary F2-isoprostane to similar levels in wild type and COMT −/− mice. *: P < 0.01. B: Representative photomicrographs of nitrotyrosine immunostaining in the outer medulla (original magnification: ×250). C: DOCA/HS induced significant increases in nitrotyrosine in wild type mice, but nitrotyrosinde increases were significantly attenuated in COMT −/− mice. *: P < 0.01 vs. control; †: P < 0.05 vs. control; ‡: P < 0.01 vs. DOCA/HS treated wild type. N = 3 in each group.