Figure 3.
DOCA/HS-induced renal macrophage infiltration was attenuated in COMT −/− mice. A: Representative photomicrographs of F4/80-positive macrophages in renal cortex and medulla (original magnification: ×250). B: There was significantly less macrophage infiltration in COMT −/−than wild type mice, and COX-2 inhibition reduced macrophage infiltration further in DOCA/HS treated COMT −/− mice.. *: P < 0.01 vs. control; †: P < 0.05 vs. control; ‡: P < 0.01 vs. DOCA/HS treated wild type. §: P < 0.01 vs. DOCA/HS treated COMT −/−.