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. Author manuscript; available in PMC: 2010 Nov 1.
Published in final edited form as: Circ Heart Fail. 2009 Sep 24;2(6):700–706. doi: 10.1161/CIRCHEARTFAILURE.109.876433

Table 2.

Average cross-sectional area of single skeletal muscle fibers from controls and heart failure patients.

Controls Heart failure # of fibers (control/heart failure)
All fibers (μm2) 5880 ± 145 6824 ± 160 * 194/200
Fibers with detectable MHC content (μm2) 5916 ± 159 6748 ± 169 * 169/161
MHC I fibers (μm2) 6613 ± 242 6538 ± 247 88/75
MHC IIA fibers (μm2) 5422 ± 210 7419 ± 305 * 50/46
MHC IIA/X fibers (μm2) 4450 ± 193 6091 ± 347 * 22/29

Data are mean ± SE and reflect the average cross-sectional area from top and side diameter measurements every 250 μm along the length of each fiber. Fibers with detectable MHC include only those with band densities greater than background, whereas the All fibers includes those with band densities equal to or less than background. There were too few MHC IIX and I/IIA fibers to permit comparisons between groups.

*

, P<0.01.