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Monitoring of GNB binding to the frameshift-site stem-loop RNA by 1H,1H TOCSY (750 MHz). A) The frameshift-site stem loop (RNA: 1.2 mm) in the absence of GNB. B) The frameshift-site stem loop (RNA: 1.2 mm) with GNB (0.75 mm). Peaks from the bound conformation are indicated with circles. C) The frameshift-site stem loop (RNA: 1.2 mm) with GNB (1.5 mm). All cross-peaks shown correspond to H5–H6 correlations of pyrimidine residues.
