Table 1.
Structures and Inhibitory Activities of Selected Compounds (μM)
| ARB Number | Structure | % Inhibition Cytopathic effect | EC50 μM | EC90 μM | IC50 μM | IC90 μM | SI50 | SI90 |
|---|---|---|---|---|---|---|---|---|
| 06-047279 |  |
71 | 2.8 | >136.9 | >136.9 | >136.9 | >49.7 | 0 |
| 06-076399 |  |
67 | 3.0 | >119.5 | >119.5 | >119.5 | >39.8 | 0 |
| 06-100378 |  |
52 | 3.1 | >144.8 | >144.8 | >144.8 | >46.7 | 0 |
| 06-067081 |  |
70 | 3.5 | >148.7 | >148.7 | >148.7 | >41.9 | 0 |
| 06-039665 |  |
55 | 4.6 | >120.8 | 5.9 | >120.8 | 1.3 | 0 |
| 06-066995 |  |
54 | 4.8 | >161.5 | >161.5 | >161.5 | >33.8 | 0 |
| 06-046310 |  |
71 | 5.4 | 20.3 | >255.5 | >255.5 | >47.3 | >32.2 |
| 06-039422 |  |
48 | 6.1 | >153.7 | >153.7 | >153.7 | >25.1 | 0 |
| 06-072422 |  |
64 | 8.2 | >161.1 | >161.1 | >161.1 | >19.6 | 0 |
| 06-070333 |  |
54 | 9.8 | 81.0 | 26.9 | >300.8 | 2.7 | >3.7 |
| 06-089154 |  |
59 | 9.8 | >151.8 | >151.8 | >151.8 | >15.4 | 0 |
| 06-100287 |  |
55 | 10.3 | >186.1 | >186.1 | >186.1 | >18.1 | 0 |
| 06-069269 |  |
53 | 11.5 | >180.5 | >180.5 | >180.5 | >15.7 | 0 |
| 06-003174 |  |
60 | 13.7 | >200.2 | 188.7 | >200.2 | 13.8 | 0 |
| 06-011087 |  |
63 | 15.2 | >238.8 | >238.8 | >238.8 | >15.7 | 0 |
| 06-015735 |  |
75 | 15.5 | >116.3 | >116.3 | >116.3 | >7.5 | 0 |
| 06-060912 |  |
80 | 16.5 | >143.9 | >143.9 | >143.9 | >8.7 | 0 |
| 06-061324 |  |
51 | 18.9 | >143.9 | >143.9 | >143.9 | >7.6 | 0 |
| 06-023109 |  |
52 | 19.0 | >193.8 | >193.8 | >193.8 | >10.2 | 0 |
| 06-018302 |  |
75 | 19.0 | >130 | >130 | >130 | >6.8 | 0 |
| 06-094955 |  |
54 | 25.0 | >248.7 | 206.5 | >248.7 | 8.3 | 0 |
| 06-001447 |  |
56 | 25.2 | >239.7 | >239.7 | >239.7 | >9.5 | 0 |