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. Author manuscript; available in PMC: 2009 Nov 25.
Published in final edited form as: J Immunol. 2009 Sep 25;183(8):5251–5260. doi: 10.4049/jimmunol.0901471

FIGURE 4.

FIGURE 4

CD1d-restricted NKT cells regulate the Ag-induced increase in pulmonary MCp numbers. A, BALB/c WT and CD1d−/− BALB/c mice were sensitized and half were challenged with aerosolized Ag as indicated. The mean (±SE) concentration of MCp/106 MNC (top panel), the number of lung MCp per mouse (middle panel), and the number of lung MNC per mouse (bottom panel) are shown from six, four, seven, and seven mice in each group, respectively. B, BALB/c mice were sensitized and treated with control IgG or anti-CD1d and either not challenged or challenged as indicated and evaluated as in A. The values are the mean (±SE) from four, four, and six mice in each group, respectively. C, BALB/c WT and Jα18−/− BALB/c mice were sensitized and half were challenged with aerosolized Ag as indicated. The mean (±SE) concentration of MCp/106 MNC (top panel), the number of lung MCp per mouse (middle panel), and the number of lung MNC per mouse (bottom panel) are shown from 7, 4, 14, and 14 mice in each group, respectively. *, p < 0.05; ***, p < 0.01; and ***, p < 0.001.