Table 3.
Comparisons of the mammalian and non-mammalian PAT proteins1
| PAT Protein | Regulated by phosphorylation | Promotes lipid storage | Recruits lipases or co-lipases | Role in intracellular trafficking | EPAT versus CPAT | PAT domain |
|---|---|---|---|---|---|---|
| Perilipin | Yes (PKA) | Yes | Yes | Yes (droplets) | CPAT | Yes |
| ADRP | Unknown | Yes | Unknown | Yes (droplets) | CPAT | Yes |
| TIP47 | Unknown | Yes | Unknown | Yes (vesicles) | EPAT | Yes |
| S3-12 | Unknown | Unknown | Unknown | Unknown | EPAT | No |
| OXPAT | Unknown | Yes | Yes | Unknown | EPAT | Yes |
| Fatvg | Unknown | Unknown | Unknown | Yes (vesicles) | Unknown | Yes |
| LSD-1 | Correlation (PKA) | Unknown | Inferred | Unknown | Unknown | Yes |
| LSD-2 | Correlation | Yes | Unknown | Yes (droplets) | Unknown | Yes |
| MPL1 | Proposed | Yes | Unknown | No | Unknown | Yes |
1
This table is intended as a summary of the text. Please refer to the text for details and references.