Table 1.

MRI prediction value for primary tumor control and disease-free survival before and during therapy

MRI Parameters	Control of Primary Tumor			Disease-Free Survival
MRI Time Point	MRI 1	MRI 2	MRI 3	MRI 1	MRI 2	MRI 3
Volume	NS	0.012	0.025	0.024	0.011	NS
Mean SI	NS	0.015	0.040	NS	NS	0.029
SI (2.5%)	NS	0.00030	0.00116	NS	NS	0.032
SI (5.0%)	NS	0.00010	0.00176	NS	NS	0.024
SI (10%)	NS	0.00124	0.00331	NS	NS	0.017
SI (15%)	NS	0.00187	0.00473	NS	NS	0.012
SI (20%)	NS	0.00402	0.00786	NS	NS	0.012

Note: Numerical values are p-values from Student t-test; NS = not significant (p>0.05). MRI 1, MRI 2, and MRI 3 were obtained before treatment, at 2–2.5 weeks, and 4–5 weeks, respectively, into the 8 weeks treatment course; SI% = percentile of signal intensity, including 2.5^th, 5^th, 10^th, 15^th and 20^th percentiles of SI, to quantify the low-DCE pixel sub-populations within the tumor.