Table 1.
MRI Parameters | Control of Primary Tumor | Disease-Free Survival | ||||
---|---|---|---|---|---|---|
MRI Time Point | MRI 1 | MRI 2 | MRI 3 | MRI 1 | MRI 2 | MRI 3 |
Volume | NS | 0.012 | 0.025 | 0.024 | 0.011 | NS |
Mean SI | NS | 0.015 | 0.040 | NS | NS | 0.029 |
SI (2.5%) | NS | 0.00030 | 0.00116 | NS | NS | 0.032 |
SI (5.0%) | NS | 0.00010 | 0.00176 | NS | NS | 0.024 |
SI (10%) | NS | 0.00124 | 0.00331 | NS | NS | 0.017 |
SI (15%) | NS | 0.00187 | 0.00473 | NS | NS | 0.012 |
SI (20%) | NS | 0.00402 | 0.00786 | NS | NS | 0.012 |
Note: Numerical values are p-values from Student t-test; NS = not significant (p>0.05). MRI 1, MRI 2, and MRI 3 were obtained before treatment, at 2–2.5 weeks, and 4–5 weeks, respectively, into the 8 weeks treatment course; SI% = percentile of signal intensity, including 2.5th, 5th, 10th, 15th and 20th percentiles of SI, to quantify the low-DCE pixel sub-populations within the tumor.