Skip to main content
. Author manuscript; available in PMC: 2009 Nov 25.
Published in final edited form as: Clin Pharmacol Ther. 2007 Aug 22;83(5):702–710. doi: 10.1038/sj.clpt.6100343

Table 2.

Change in lipid concentrations after 4 months of tamoxifen treatment

All subjects (N=176)
 Premenopausal (N=55)
 Postmenopausal (N=101)
Lipid particle Mean change (95% CI)a P-valueb Mean change (95% CI) P-value Mean change (95% CI) P-value
T-Chol −17.7 (−24.7, 10.7) <0.0001 −12.0 (−20, −4) 0.004 −24.1 (−30, −18) <0.0001
TG 24.4 (−4.4, 44.4) 0.006 41.3 (11.2, 71.5) 0.009 17.4 (−4.6, 39.4) 0.14
HDL 0.5 (−0.5, 1.5) 0.54 0.7 (−2.1, 3.5) 0.60 −0.01 (−2.0, 2.0) 0.99
LDL −23.5 (−13.5, 33.5) <0.0001 −18.7 (−26.3, 11.1) <0.0001 −26.5 (−31.1, −20.9) <0.0001

CI, confidence interval; HDL, high-density lipoprotein; LDL, low-density lipoprotein; T-Chol, total cholesterol; TG, triglycerides.

a

Mean change in lipid particle concentration is shown in mg/dl with 95% CI given in parentheses.

b

P-values are calculated for difference between baseline and lipid concentrations following 4 months of tamoxifen treatment.