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Ratios of intracellular concentrations between FD-4 and FD-2000 as a function of the fractional area of pores in the permeabilized membrane cap (α) for different pore opening periods (T): (a) T = 0.1 msec; (b) T = 1 msec; and (c) T = 10 msec. The ratios depended on average pore diameter that was chosen to be 100, 200, or 500 nm in the simulation.
