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. Author manuscript; available in PMC: 2010 Dec 1.
Published in final edited form as: JALA Charlottesv Va. 2009 Dec 1;14(6):331–340. doi: 10.1016/j.jala.2009.06.003

Figure 1.

Figure 1

Numerical simulation of long-range and short-range magnetic field gradients in a microfluidic device designed for magnetophoretic separation. a) Long-range gradients are produced by a series of external permanent magnets, with the magnitude of the -y direction gradient exceeding 200 T/m over the cross-section of a microfluidic channel located 0.5 mm above the surface of the magnets. b) An abrupt change in relative permittivity (μr) between microfabricated nickel features (μr ~200) and the biological sample (μr ~1) creates an extremely large short-range magnetic field gradient. The magnitude of this gradient is > 104 T/m within 8 μm of the microfabricated features. Image adapted from Adams et al.35 with permission. ©PNAS 2008.