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. 2009 Sep 23;29(38):11867–11879. doi: 10.1523/JNEUROSCI.0819-09.2009

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Copyright © 2009 Society for Neuroscience 0270-6474/09/2911867-13$15.00/0

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Figure 5. — The time-dependent variance of the single-photon responses in wild-type, Arr1 ^+/−, GRK1 ^+/−, and GRK1 ^+/− Arr1 ^+/− rods. Left column superimposes 10 isolated single-photon responses from a wild-type and a Arr1 ^+/− rod (A), a GRK1 ^+/− rod (B), and a GRK1 ^+/− Arr1 ^+/− rod (C). Right column compares the squared mean (thin trace) and the time-dependent variance (thick trace) of wild-type rods (gray; n = 29) with Arr1 ^+/− (red; n = 41) rods (A), GRK1 ^+/− (blue; n = 30) rods (B), and GRK1 ^+/− Arr1 ^+/− (green; n = 40) rods (C). The responses in each cell were normalized by the amplitude and time-to-peak of the average single-photon response of the cell to facilitate comparison of the time course of the variance.