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. Author manuscript; available in PMC: 2010 Oct 15.

Published in final edited form as: Free Radic Biol Med. 2009 Jul 17;47(8):1147–1153. doi: 10.1016/j.freeradbiomed.2009.07.019

Table 2.

Rat serum and liver metabolites 30 minutes after LA (100 mg/kg) (N=6) vs. DHLA 100 mg/kg (N=5) IP injection

	Serum (uM or nM^*)			Liver (nmol/g)
	LA	DHLA		LA	DHLA
Metabolite
	Mean (SD)	Mean (SD)	p	Mean (SD)	Mean (SD)	p
Lipoic Acid	243 (85)	196 (44)	0.272	114 (46)	77 (15)	0.107
tHcys	9.4 (1.2)	6.8 (1.5)	0.011	35.1 (5.6)	24.0 (4.5)	0.006
SAH^*	233 (58)	409 (156)	0.083	82 (7)	73 (9)	0.076
SAM^*	136 (15)	188 (39)	0.014	9 (2)	7 (2)	0.051
Cysteine	69 (5)	72 (16)	0.708	770 (57)	845 (65)	0.070
Methionine	80.0 (9.6)	86.3 (7.1)	0.257	427 (35)	483 (52)	0.062
N-methylglycine	3.1 (0.9)	4.2 (0.5)	0.040	49.6 (12.4)	71.4 (10.3)	0.012

^*

SAH and SAM are nmol/L