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. Author manuscript; available in PMC: 2010 Oct 15.

Published in final edited form as: Free Radic Biol Med. 2009 Jul 17;47(8):1147–1153. doi: 10.1016/j.freeradbiomed.2009.07.019

Table 3.

Rat Serum and liver metabolites 60 minutes after Mesna (150 mg/kg) (N=5) vs. Control (N=6) IP injection

	Serum (uM or nM^*)			Liver (nmol/g)^†
	Mesna	Control		Mesna	Control
	Mean (SD)	Mean (SD)	p.	Mean (SD)	Mean (SD)	p.
tHcys	0.9 (0.1)	2.9 (0.8)	0.002	23.4 (12.1)	19.2 (4.1)	0.485
SAH^*	128 (99)	69 (9.2)	0.253	ND^a	ND
SAM^*	252 (44)	234 (24)	0.459	ND	ND
Cysteine	40 (8)	234 (46)	0.001	1003 (153)	963 (197)	0.725
Methionine	60.0 (9.5)	63.0 (6.4)	0.678	248 (38)	257 (42)	0.743
Cystathionine	587 (76)	872 (181)	0.010	13.6 (7.1)	12.2 (5.9)	0.746

^*

Serum SAH, SAM and cystathionine are nmol/L

^†

N = 5 (Mesna) and N = 5 (Control) for liver values

^a

ND = Not Determined