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. Author manuscript; available in PMC: 2009 Nov 25.
Published in final edited form as: Antivir Ther. 2009;14(7):891–898. doi: 10.3851/IMP1420

FIG. 3.

FIG. 3

Effect of treatment with BCX 2798 on virus titers in mice infected with 100 PFU of rSeV(hPIV-1HN). BCX 2798 at dosages of 0.1 (-■-), 1 (-▲-) and 10 (-○-) mg/kg/d was administered intranasally to 129x1/SvJ mice starting at either 24 h (A) or 48 h (B) after infection (treatment for five consecutive days) or 72 h (C) after infection (treatment for four consecutive days). Control infected mice were treated with PBS alone (- ◆ -). The mean virus lung titers from six to nine mice from at least two independent in vivo experiments are presented. The averages for each group are plotted with error bars indicating the SEM. *P<0.05 compared with the control group; one-way ANOVA model.