TABLE 2.
Demographic and Clinical Measures in LLD Treatment Responders by Cognitive Classification
| MCI-Amnestic (N = 26) | MCI-Nonamnestic (N = 15) | Cognitively Normal (N = 57) | F or χ2 | df | p | |
|---|---|---|---|---|---|---|
| Age | 76.4 (5.5) | 76.7 (7.4) | 72.3 (5.9) | 5.78 | 2.95 | 0.004 |
| Men, % (n) | 23 (6) | 20 (3) | 21 (12) | 0.06 | 2 | 0.97 |
| White, % (n) | 88 (23) | 73 (11) | 95 (54) | 6.00 | 2 | 0.049 |
| Education in years | 12.8 (2.0) | 13.2 (2.5) | 14.1 (2.8) | 2.48 | 2.95 | 0.090 |
| CIRS-G total | 10.3 (2.5) | 11.1 (3.1) | 10.3 (3.5) | 0.38 | 2.89 | 0.69 |
| Initial HDRS | 19.0 (3.2) | 18.5 (3.0) | 18.2 (3.3) | 0.55 | 2.95 | 0.58 |
| Residual HDRS | 6.2 (2.4) | 6.1 (2.1) | 5.3 (2.7) | 1.36 | 2.95 | 0.26 |
| Recurrent, % (n) | 48 (10) | 38 (5) | 64 (30) | 338 | 2 | 0.18 |
| Age of onset | 58.5 (20.0) | 63.3 (24.3) | 54.2 (18.9) | 1.34 | 2.95 | 0.27 |
| Late onset, % (n) | 58 (15) | 80 (12) | 49 (28) | 4.63 | 2 | 0.10 |
| MMSE | 28.2 (1.3) | 28.1 (1.5) | 28.9 (1.2) | 3.95 | 2 | 0.02 |
Notes: Comparison of LLD patients diagnosed with No Cognitive disorder, MCI-Amnestic, and MCI-Nonamnestic, after treatment response, on basic demographic and clinical variables. The dementia group was excluded due to small sample size.
CIRS-G: Cumulative Illness Rating Scale for Geriatrics; HDRS: Hamilton Depression Rating Scale; MMSE: Mini Mental Status Examination.