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. Author manuscript; available in PMC: 2009 Nov 25.
Published in final edited form as: Front Biosci. 2005 May 1;10:1597–1606. doi: 10.2741/1643

Figure 2.

Figure 2

Pertussis toxin inhibits endothelial [Ca2+]i responses. HUVEC were preincubated with 0.5 μg/ml PT in culture medium for 2 hr. Melanoma cell contact induced an increase 121 ± 22 % (n = 11) in peak [Ca2+]i magnitude in untreated endothelial cells, whereas the magnitude reduced to 51 ± 19 % (n = 12) in PT-pretreated cells. The population of responding cells decreased to 59 ± 9 % (n = 12) compared with 80 ± 4 % (n = 11) in untreated endothelial cells. Results are presented with mean ± SEM.