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. 2009 Sep 15;30(11):1923–1926. doi: 10.1093/carcin/bgp200

Table I.

Summary of intestinal tumor development in mutant mice after feeding sulindac

	Apc1638^N/+	Mlh1^+/−	Mlh1^+/−/Apc1638^N/+
	Sulindac added to AIN-76A diet	Sulindac added to AIN-76A diet	Sulindac added to AIN-76A diet
Tumor incidence
Small intestine	−	+	−
Colon	+	+	+
Tumor multiplicity
Small intestine	−	+	−
Colon	+	+	+
Tumor volume
Small intestine	−	+	−
Colon	+	+	+

Decreased (−) or increased (+) tumor incidence, multiplicity or volume compared with mice fed unmodified control AIN-76A diet.