Table 2.
Baseline demographics of patients enrolled in study according to treatment for toenail onychomycosis
| Parameter | Terbinafine 12 weeks | Terbinafine 16 weeks | Itraconazole 3 cycles | Itraconazole 4 cycles | All patients | Overall P value |
|---|---|---|---|---|---|---|
| No of patients | 124 | 120 | 126 | 126 | 496 | |
| Mean (SD) age (years) | 50.1 (12.3) | 50.9 (13.1) | 50.7 (12.6) | 48.6 (13.1) | 50.1 (12.8) | 0.4549 |
| Proportion (%) of women | 42.7 | 43.3 | 42.9 | 38.9 | 41.9 | 0.8637 |
| Race (% white; % Asian/Oriental) | 97.6; 2.4 | 99.2; 0.8 | 99.2; 0.8 | 98.4; 1.6 | 98.6; 1.4 | 0.736 |
| Dermatophytes (%): | ||||||
| T rubrum | 91.9 | 85.8 | 88.9 | 90.5 | 89.3 | 0.3549 |
| T rubrum plus non-dermatophyte mould | 1.6 | 2.5 | 1.6 | 0.8 | 1.6 | |
| T rubrum plus T mentagrophytes | 2.4 | 0.6 | ||||
| T mentagrophytes | 6.5 | 11.7 | 9.5 | 6.3 | 8.5 | |
| Mean (SD) No of infected toenails | 5.6 (2.8) | 6 (2.8) | 5.6 (2.9) | 5.9 (2.9) | 5.8 (2.8) | 0.5599 |
| Mean (SD) proportion (%) of target nail involvement | 73.7 (25.5) | 69.9 (25.3) | 69.7 (26.2) | 68.5 (29.00) | 70.4 (26.6) | 0.4455 |
| Mean (SD) duration (years) of current episode | 11.8 (10.3) | 10.5 (9.7) | 10.4 (8.8) | 9.9 (9.30) | 10.6 (9.50) | 0.4847 |