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. Author manuscript; available in PMC: 2010 Nov 1.
Published in final edited form as: Magn Reson Med. 2009 Nov;62(5):1091–1098. doi: 10.1002/mrm.22120

Figure 5.

Figure 5

(A) Fractional enrichment of the several metabolites following the delivery of [3-13C] pyruvate to primary cultured prostate cancer cells derived from five different prostate cancer patients. The prostate cancers from patients 1-3 had a Gleason score of 3+3 and the patients 4 and 5 had a Gleason score of 4+3. (B) The average and standard deviation of the concentration of the 13C pool for each of the metabolites is also presented. While all the metabolites were enriched above natural abundance, the [3-13C] pyruvate was converted to glutamate more than any of the other metabolites during a 2 hour exposure to the pyruvate. Pt: Patient; Ala: Alanine; Glut: Glutamate; Asp: Aspartate; Lac: Lactate.