Table 2.
EASE analysis of dnCDK9 modulated genes.
| Downregulated genes | ||
|---|---|---|
| GO Biological Process | EASE score |
# genes |
| Transcription | 2.0E-4 | 22 |
| Regulation of transcription | 3.2E-4 | 21 |
| Cell organization and biogenesis | 6.1E-4 | 16 |
| Nuclear transport | 8.6E-4 | 5 |
| mRNA metabolism | 2.3E-3 | 6 |
| mRNA export from nucleus | 8.6E-3 | 3 |
| mRNA processing | 8.9E-3 | 5 |
| Regulation of progression through cell cycle | 9.7E-3 | 7 |
|
Upregulated genes | ||
| GO Biological Process |
EASE score |
# genes |
| Regulation of protein kinase activity | 1.4E-4 | 7 |
| Regulation of transfer activity | 1.5E-4 | 7 |
| Cell organization and biogenesis | 3.0E-3 | 19 |
| Cell cycle | 3.1E-3 | 12 |
| Biopolymer metabolism | 3.3E-3 | 29 |
| Response to chemical stimulus | 8.2E-3 | 8 |
Biological Process are listed for genes with a p value<0.01