Table 2.

Baseline Serum Lipids, in Tertiles, Predicting Impairment on HVLT-Delayed Recall^a

			Lipids in Tertiles
		Total N	Categorical		2 vs. 1		3 vs. 1
Lipid	Events		HR (95% CI)	p-value	HR (95% CI)	p-value	HR (95% CI)	p-value
Total SM	23	89	1.88 (1.05-3.38)	0.034	2.29 (0.58-9.03)	0.238	3.83 (1.04-14.08)	0.043
Ceramides
C16:0b	21	83	2.12 (1.17-3.84)	0.013	15.36 (1.86-126.68)	0.011	12.39 (1.57-97.97)	0.017
C18:0	18	69	1.89 (0.95-3.77)	0.071	9.03 (1.06-76.67)	0.044	7.35 (0.88-61.18)	0.065
C20:0	20	70	1.61 (0.90-2.86)	0.108	3.64 (0.91-14.54)	0.068	3.14 (0.81-12.16)	0.098
C22:0	20	86	2.12 (1.10-4.08)	0.025	no events in lowest tertile
C24:1	23	88	1.67 (0.96-2.88)	0.069	6.32 (1.35-29.66)	0.019	4.94 (1.05-23.37)	0.044
C24:0b	23	90	2.23 (1.23-4.05)	0.008	12.75 (1.54-105.41)	0.018	13.25 (1.69-103.96)	0.014
Galactosyl C12:0	21	73	1.79 (0.99-3.24)	0.053	2.79 (0.67-11.59)	0.158	3.71 (0.98-14.07)	0.054
Lactosyl C12:0	19	67	2.26 (1.15-4.44)	0.018	9.58 (1.14-80.43)	0.037	10.48 (1.28-85.72)	0.028
Stearoyl	23	87	1.86 (1.05-3.27)	0.032	13.71 (1.75-107.44)	0.013	9.83 (1.24-78.11)	0.031
Sulfatide	20	76	2.06 (1.08-3.96)	0.029	1.75 (0.43-7.13)	0.433	4.04 (1.07-15.28)	0.040
SM/Cholesterol ratio	22	88	1.66 (0.94-2.92)	0.081	3.03 (0.81-11.33)	0.100	3.35 (0.89-12.59)	0.074
Total cholesterol	23	89	0.86 (0.64-1.15)	0.317	0.74 (0.44-1.25)	0.263	0.76 (0.43-1.34)	0.345

HR = Hazard Ratio; CI = Confidence Interval

^aModels control for baseline age, blood glucose level, and BMI

^b1 case in lowest tertile