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. Author manuscript; available in PMC: 2010 Nov 23.
Published in final edited form as: Vaccine. 2009 Sep 26;27(50):7110–7115. doi: 10.1016/j.vaccine.2009.09.056

TABLE 1.

Data Inputs for Model Variables

95% Range
Description (units) Mean Source
Lower Limit Upper Limit
COSTS
Influenza Vaccine ($US) 15.00 - - [23]
Vaccine Administration ($US) 5.00 - - Estimate
Anti-Viral medication: Oseltamivir ($US) 99.32 77.32 121.32 [23]
Influenza Treatment:
    Over the Counter Medications ($US) 15.61 10.30 20.91 [23]
    Outpatient Visit ($US) 151.38 114.94 187.81 [24]
    Productivity Loss for Outpatient Visit ($US) 64.08 54.00 74.16 [25]
    Hospitalization ($US), 65-84 years old 4723 4382 5064 [26]
    Hospitalization ($US), >85 years old 5146 5406 5886 [26]
    Death in Hospital ($US) 5,000 - - [27]
    Treatment of Vaccine Side Effects ($US) 0.76 0.68 3.82 [28]
DURATIONS
Influenza (days) 7 - - [27, 29, 30]
Clinic Visit (hours) 4 - - [27, 29, 30]
UTILITIES
One Year of Life for Older Adult (QALY) 0.84 - - [10]
Utility/Day
    Influenza no Hospitalization (QALY) 0.65 0.49 0.81 [11, 31]
    Influenza with Hospitalization (QALY) 0.50 0.38 0.63 [11, 31]
    Vaccine Side Effects (QALY) 0.95 0.71 1.00 [11]
PROBABILITIES
Clinical Outcomes without Vaccination
    Influenza throughout the Year 0.125 0.05 0.20 [14]
    Clinic Visit Given Influenza 0.40 - - [14]
    Hospitalization Given Influenza 0.04 0.01 0.07 [14]
Clinical Outcomes with Vaccination
    Reduction in Hospitalization 0.565 0.45 0.68 [14]
    Reduction in Mortality 0.21 0 0.42 [14]
    Side Effects 0.05 - - [14]
Decrease in Attack Rate from Earlier Vaccination 0.00 0.00 0.25 [13, 14]