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. Author manuscript; available in PMC: 2010 Nov 24.
Published in final edited form as: Biochemistry. 2009 Nov 24;48(46):10976–10987. doi: 10.1021/bi901291c

Figure 8.

Figure 8

Representation of cross-linking results of TM7 and helical wheel presentation of TM1 and TM7 in Ste2p. A. Summary of TM7 cysteine cross-linking results. The horizontal lines represent the boundary of the cell membrane. Residues indicated by a circle filled in gray when mutated to Cys are involved in dimer formation, whereas those residues shown in a box do not form disulfide bonds. Residues marked by an * compensate for the non-functional Y266C mutation. B. Helical wheel presentation of TM1 and TM7. Residues indicated by a circle filled in gray are involved in dimer formation as found in this study. Residues marked by an X are important for ligand binding.