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. Author manuscript; available in PMC: 2010 Dec 1.
Published in final edited form as: Exp Eye Res. 2009 Jul 29;89(6):898–904. doi: 10.1016/j.exer.2009.07.015

Table 4.

Truncation sites of Cx46:

Truncation sites Source
Cortex Nucleus
G121 Trypsin (108-121) Trypsin (108-121), Glu-C (109-121)
H122 Trypsin (108-122) Trypsin (108-121), Glu-C (109-122)
D124 Trypsin (116-124), Lys C (116-124) Trypsin (116-124), N/A
G251 N/D Trypsin (243-251)
L255 N/D Trypsin (243-255)
N259 N/D Trypsin (243-259)
I267 N/D Trypsin (243-267)
F269 N/D Trypsin (243-269)
Y273 N/D Trypsin (243-273)
A274 N/D Trypsin (243-274)
S278 N/D Trypsin (243-278)
S284 N/D Trypsin (243-284)
A285 N/D Trypsin (243-285)
E344 Trypsin (332-344), Glu C (N/A) N/D
G347 Trypsin (332-347) N/D
Q352 Trypsin (332-352) N/D
G2 N/D Trypsin (3-9), Glu-C (3-12)

N/D: not detected; N/A: enzyme cleavage site, therefore, cannot be used to detect truncation at this site