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. Author manuscript; available in PMC: 2010 Jul 1.
Published in final edited form as: Chem Res Toxicol. 2009 Jul;22(7):1264–1276. doi: 10.1021/tx9000754

Table 1.

Experimental design. Tumor incidence is summarized by dose and quartile. A complete dataset at the tank level is included in the supporting information (Table S-1).

Experiment
quarter
DBP
dose
(ppm
diet)
Replicate
groups
necropsied
Animals
necropsied
Histological
liver
neoplasia
Incidence Stomach
neoplasia
Incidence
1 0 23 2097 2 0.00095 5 0.00236
2 0 22 2056 4 0.00195 5 0.00236
3 0 25 2348 2 0.00085 1 0.00043
4 0 21 1862 2 0.00107 4 0.00200
1 0.45 24 2139 1 0.00047 9 0.00420
2 0.45 22 2021 4 0.00198 3 0.00148
3 0.45 25 2380 2 0.00084 5 0.00210
4 0.45 25 2208 5 0.00226 3 0.00136
1 1.27 14 1280 4 0.00313 2 0.00138
2 1.27 18 1672 5 0.00299 4 0.00234
3 1.27 19 1814 1 0.00055 3 0.00165
4 1.27 19 1663 2 0.00120 3 0.00180
1 3.57 8 737 9 0.01221 4 0.00513
2 3.57 14 1253 11 0.00878 7 0.00559
3 3.57 14 1327 8 0.00603 2 0.00151
4 3.57 14 1218 9 0.00739 3 0.00246
1 10.1 3 275 9 0.03273 1 0.00364
2 10.1 4 361 25 0.06925 1 0.00277
3 10.1 5 488 27 0.05533 2 0.00410
4 10.1 5 434 24 0.05530 4 0.00922
1 28.4 2 182 25 0.13736 11 0.06044
2 28.4 3 278 73 0.26259 11 0.03957
3 28.4 4 387 48 0.12403 19 0.04909
4 28.4 4 364 95 0.26099 15 0.04121
1 80 2 190 88 0.46316 65 0.342
2 80 2 186 91 0.48925 46 0.247
3 80 3 292 144 0.49315 76 0.260
4 80 3 263 138 0.52471 86 0.327
1 225 1 93 63 0.67742 68 0.731
2 225 1 85 56 0.65882 71 0.835
3 225 2 180 100 0.55556 127 0.706
4 225 2 183 99 0.54098 129 0.705