Table 3.

Effect of MBG, Spironolactone, and Canrenone on Radiolabeled Proline Incorporation

Group (N)	Proline Incorporation (Fraction of Control Values)
Control (64)	1.00±0.02
MBG, 1 nmol/L (20)	1.58±0.06*
MBG, 10 nmol/L (36)	1.67±0.04*
MBG, 100 nmol/L (8)	1.64±0.10*
Aldosterone, 1 nmol/L (24)	1.04±0.03
Aldosterone, 10 nmol/L (10)	0.93±0.08
Aldosterone, 100 nmol/L (24)	0.97±0.04
Spironolactone, 100 nmol/L (20)	0.85±0.03*
Spironolactone, 1 μmol/L (32)	0.80±0.05*
Canrenone, 100 nmol/L (12)	0.82±0.04*
Canrenone, 1 μmol/L (12)	0.66±0.05*
MBG, 1 nmol/L+spironolactone, 100 nmol/L (20)	0.98±0.04†
MBG, 1 nmol/L+spironolactone, 1 μmol/L (20)	0.80±0.03*†
MBG, 1 nmol/L+canrenone, 100 nmol/L (12)	0.76±0.06*†
MBG, 1 nmol/L+canrenone, 1 μmol/L (12)	0.65±0.07*†
MBG, 100 nmol/L+spironolactone, 100 nmol/L (8)	1.65±0.05*
MBG, 100 nmol/L+canrenone, 100 nmol/L (8)	1.72±0.06*

^*P<0.01 vs control.

^†P<0.01 vs MBG, 1 nmol/L.