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. Author manuscript; available in PMC: 2010 Nov 15.
Published in final edited form as: Clin Cancer Res. 2009 Oct 27;15(22):6912–6920. doi: 10.1158/1078-0432.CCR-09-1698

Table 1.

HPRT gene mutation rate (6-TG resistance)

Cells Treatment Mutation rate Induced mutation rate
HCT116vector No radiation 195 ± 18/1×106 -
LDR-IR 4.5cGy/h 326 ± 33/1×106 131/1×106
HCT116MLH1 No radiation 3.8 ± 0.8/1×106 -
LDR-IR 4.5cGy/h 10.2 ± 3.1/1×106 6.4/1×106