Table 1.
Induction of MDSCs and M2 following infection
| Infection | MDSC | M2 | References |
|---|---|---|---|
| Helminths/extracellular parasitic worms: Require Th2 responses to clear infection | |||
| Schistosoma mansoni | CD11b+GR1+F4/80+NO | Arg1,MR,Fizz1,Ym1, IL-10,TGFb | [3,8,11] |
| Taenia crassiceps | CD11b+GR1+NO | Arg1,MR,Fizz1,Ym1 | [3,11] |
| Bacteria: Require Th1or Th17 response to clear infection | |||
| Porphyromonas gingivalis | CD11b+GR1+ | unknown | [11] |
| Mycobacterium tuberculosis | CD11b+iNOS | Arg1,MR,IL10,IL-1Ra | [13,15,38,102] |
| Mycobacterium bovis (BCG) | CD11b+GR1+ | Arg1 | [13,103] |
| Helicobactor pylori | CD11b+ | Arg2 | [13,104,105] |
| Viruses: Require Th1 response to clear infection | |||
| Influenza A | CD11b+ NOS | Arg1 | [19,106] |
| Coxsackievirus B3 | CD11b+GR1+F4/80+ | Arg1,MR,Ym1,IL-10,IL-1 | [50] |
| Other: | |||
| Candida albicans | CD11b+GR1+CD80+ | MR,Dectin-1 | [23,107,108] |
| Trypanosoma cruzi | CD11b+GR1+iNOS/NO | Arg1 | [11,18,109] |
| Toxoplasma gondii | CD11b+GR1+F4/80+iNOS | Arg1 | [13,20] |