Table 2.

Spearman correlations of individual and grouped urinary estrogens and estrogen metabolites (EM), expressed as absolute concentrations and percent of total EM for the average of 3 collections.

					Cat	2Cat			4Cat	Me Cat	Me-2Cat				Me-4Cat			2Path	4Path	16Path						Total EM
		Parent	E1	E2			2OHE1	2OHE2	4OHE1			2MeE1	2MeE2	2OH3Me		4MeE1	4MeE2				16aOHE1	E3	17EpiE3	16KetoE2	16EpiE3
Parent EM		1.0	0.96	0.79	0.32	0.32	0.33	0.27	0.32	0.48	0.48	0.45	0.42	0.45	0.38	0.37	0.11	0.36	0.33	0.33	0.28	0.25	0.26	0.36	0.43	0.64
	E1	0.93	1.0	0.62	0.40	0.40	0.41	0.36	0.39	0.52	0.52	0.48	0.50	0.49	0.32	0.33	0.07	0.44	0.40	0.30	0.29	0.20	0.25	0.35	0.41	0.66
	E2	0.73	0.48	1.0	0.06	0.06	0.07	0.01	0.10	0.27	0.26	0.26	0.12	0.23	0.40	0.35	0.12	0.10	0.10	0.32	0.19	0.28	0.21	0.30	0.35	0.46
Catechol EM		−0.30	−0.24	−0.41	1.0	1.00	0.99	0.89	0.89	0.64	0.63	0.65	0.66	0.44	0.31	0.30	0.15	0.99	0.89	−0.19	−0.20	−0.24	−0.10	−0.10	0.03	0.65
2-Catechol EM		−0.30	−0.24	−0.42	0.99	1.0	0.99	0.90	0.86	0.62	0.62	0.64	0.67	0.43	0.29	0.29	0.15	0.99	0.86	−0.18	−0.20	−0.24	−0.10	−0.09	0.03	0.65
	2OHE1	−0.29	−0.23	−0.41	0.99	1.00	1.0	0.87	0.87	0.64	0.64	0.66	0.67	0.45	0.29	0.29	0.15	0.99	0.87	−0.18	−0.19	−0.24	−0.09	−0.09	0.02	0.65
	2OHE2	−0.31	−0.23	−0.42	0.81	0.83	0.79	1.0	0.76	0.56	0.56	0.57	0.67	0.41	0.25	0.25	0.06	0.89	0.77	−0.13	−0.19	−0.17	−0.06	−0.06	0.09	0.60
4-Catechol EM	4OHE1	−0.14	−0.11	−0.25	0.82	0.76	0.77	0.58	1.0	0.60	0.60	0.60	0.56	0.43	0.30	0.30	0.06	0.87	1.00	−0.21	−0.21	−0.25	−0.10	−0.16	−0.01	0.58
Me Catechol EM		0.28	0.26	0.12	0.37	0.36	0.37	0.30	0.38	1.0	1.00	0.98	0.76	0.85	0.46	0.43	0.20	0.70	0.61	−0.18	−0.11	−0.26	−0.04	−0.05	−0.07	0.45
Me 2-Catechol EM		0.28	0.27	0.12	0.37	0.36	0.37	0.30	0.37	1.00	1.0	0.98	0.76	0.84	0.44	0.41	0.18	0.70	0.61	−0.18	−0.11	−0.27	−0.05	−0.06	−0.07	0.45
	2MeE1	0.24	0.21	0.12	0.41	0.40	0.41	0.33	0.40	0.97	0.97	1.0	0.73	0.77	0.41	0.39	0.19	0.71	0.62	−0.20	−0.12	−0.28	−0.07	−0.09	−0.09	0.44
	2MeE2	0.13	0.21	−0.12	0.39	0.40	0.40	0.44	0.30	0.70	0.70	0.65	1.0	0.59	0.32	0.32	0.10	0.71	0.57	−0.11	−0.04	−0.18	−0.06	0.00	0.12	0.50
	2OH3Me	0.31	0.30	0.17	0.15	0.13	0.14	0.15	0.18	0.81	0.82	0.73	0.46	1.0	0.41	0.37	0.19	0.50	0.45	−0.08	−0.01	−0.17	0.04	0.03	0.01	0.32
Me 4-Catechol EM		0.24	0.14	0.29	0.03	0.02	0.03	−0.01	0.02	0.36	0.36	0.33	0.21	0.36	1.0	0.93	0.48	0.33	0.32	0.12	0.06	0.06	−0.01	0.16	0.19	0.36
	4MeE1	0.26	0.17	0.27	0.03	0.02	0.03	0.01	0.03	0.36	0.36	0.32	0.25	0.35	0.94	1.0	0.22	0.32	0.32	0.11	0.03	0.08	0.03	0.13	0.18	0.33
	4MeE2	0.04	−0.01	0.07	0.02	0.03	0.04	−0.05	−0.02	0.21	0.21	0.22	0.09	0.18	0.51	0.24	1.0	0.17	0.07	0.05	0.08	−0.03	−0.09	0.08	0.08	0.17
2-Pathway EM		−0.27	−0.22	−0.38	0.98	0.99	0.99	0.82	0.77	0.46	0.46	0.50	0.47	0.22	0.07	0.07	0.05	1.0	0.87	−0.19	−0.19	−0.25	−0.10	−0.09	0.03	0.66
4-Pathway EM		−0.13	−0.11	−0.25	0.82	0.76	0.77	0.59	1.00	0.39	0.38	0.40	0.31	0.19	0.06	0.06	0.00	0.77	1.0	−0.20	−0.20	−0.25	−0.10	−0.15	0.00	0.58
16-Pathway EM		−0.03	−0.06	0.12	−0.88	−0.87	−0.88	−0.69	−0.76	−0.53	−0.53	−0.56	−0.47	−0.28	−0.14	−0.15	−0.04	−0.90	−0.77	1.0	0.85	0.95	0.55	0.87	0.82	0.48
	16αOHE1	−0.01	0.04	−0.01	−0.75	−0.74	−0.74	−0.63	−0.65	−0.35	−0.35	−0.38	−0.30	−0.16	−0.16	−0.20	0.05	−0.76	−0.66	0.83	1.0	0.74	0.49	0.79	0.66	0.37
	E3	−0.08	−0.13	0.11	−0.82	−0.81	−0.82	−0.63	−0.71	−0.55	−0.55	−0.57	−0.48	−0.33	−0.18	−0.16	−0.11	−0.84	−0.71	0.95	0.70	1.0	0.45	0.77	0.78	0.40
	17EpiE3	0.07	0.04	0.11	−0.48	−0.47	−0.47	−0.39	−0.43	−0.24	−0.23	−0.28	−0.28	−0.05	−0.09	−0.08	−0.07	−0.48	−0.43	0.52	0.47	0.39	1.0	0.53	0.35	0.30
	16KetoE2	0.04	0.03	0.16	−0.78	−0.77	−0.77	−0.64	−0.70	−0.35	−0.35	−0.39	−0.34	−0.11	0.00	−0.02	0.04	−0.79	−0.71	0.86	0.77	0.74	0.48	1.0	0.72	0.48
	16EpiE3	0.00	−0.02	0.11	−0.63	−0.63	−0.64	−0.41	−0.55	−0.46	−0.46	−0.49	−0.23	−0.27	−0.03	−0.05	0.02	−0.66	−0.55	0.74	0.53	0.72	0.25	0.60	1.0	0.57

Note: Correlations in bottom left of table are EM expressed as % of total EM; Correlations in top right are expressed as absolute concentrations of EM. Correlations ≥|0.40| are bolded.