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. Author manuscript; available in PMC: 2010 Nov 1.
Published in final edited form as: Clin Cancer Res. 2009 Oct 27;15(21):6551–6559. doi: 10.1158/1078-0432.CCR-09-1067

Figure 5. Elevated plasma IL-15 levels are associated with increased GAA-reactive CD8+ T cells in mice treated with 1D11 and GAA-vaccines.

Figure 5

On day 35, peripheral blood samples and SPCs were collected from glioma-bearing treated mice. A, plasma IL-15 levels were evaluated by ELISA. B and C, (B) proportions of EphA2671-679 tetramer+/CD8+ cells in lymphocyte-gated CD8+ cells, and (C) absolute numbers of EphA2671-679 tetramer+/CD8+/CD44high/CD62Lhigh (central memory) or EphA2671-679 tetramer+/CD8+/CD44high/CD62Llow (effector memory) cells per 1×105 SPCs were analyzed by flow cytometric analyses. For A-C, the results represent the mean ± SD of samples from three mice per group. *, p < 0.05 and **, p < 0.01 for indicated comparisons.