Skip to main content
. Author manuscript; available in PMC: 2010 Nov 1.
Published in final edited form as: Trends Pharmacol Sci. 2009 Sep 15;30(11):581–591. doi: 10.1016/j.tips.2009.08.002

Figure 3. Computer modeling of opioid interaction with the TLR4-MD2 complex.

Figure 3

In silico docking of (-)-morphine to the 3D crystalline structure of the human MD2 (blue) and TLR4 (green) complex demonstrates that the preferred binding conformation of (-)-morphine is to the LPS binding domain of MD2.