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APOE Genotype and PTS
| PTS Subjects | No PTS | |
|---|---|---|
| ε2,3 or ε3,3 | 18 (72.0 %) | 18 (69.2 %) |
| ε2,4 or ε3,4 or ε4,4 | 7 (28.0 %) | 8 (30.8%) |
In most populations the allele frequency for APOE2, APOE3 and APOE4 are 0.075, 0.774 and 0.15. Therefore we would expect 72% of patients to not carry the APOE4 allele. There was no statistically significant difference in the frequency of APOE4 allele in patients who developed PTS compared to the control non PTS patients. (χ2 = 0.047, DF=1, p=0.828)
