. Author manuscript; available in PMC: 2009 Nov 26.

Published in final edited form as: Brain Behav Immun. 2008 Aug 3;22(8):1257–1262. doi: 10.1016/j.bbi.2008.07.010

Table 1.

Differences in Indices of Immune Status and Tryptophan Degradation as a Function of ART Non-Adherence and Stimulant Use Categories

	≥ 90% ART Adherence (N = 80)	< 90 % ART Adherence (N = 46)	No Stimulant Use (N = 83)	Monthly Stimulant Use (N = 44)	Weekly Stimulant Use (n =27)
	M (SD)	M (SD)	M (SD)	M (SD)	M (SD)
HIV Viral Load (log₁₀)	2.76 (1.23)^a	3.49 (1.27)^a	2.92 (1.25)^c	3.25 (1.34)	3.65 (1.31)^c

CD4+ Count	498.78 (308.71)	438.57 (316.03)	494.81 (297.38)	436.07 (335.64)	435.31 (365.12)
Neopterin (log₁₀)	1.00 (.24)^a	1.12 (.26)^a	1.01 (.25)^b,^c	1.12 (.23)^b	1.18 (.22)^c
Tryptophan	49.07 (11.20)	45.99 (13.23)	49.12 (12.70)^c	45.31 (10.38)	40.66 (8.25)^c
Kynurenine (square root)	1.47 (.30)	1.53 (.39)	1.53 (.36)	1.43 (.28)	1.41 (.25)
Kynurenine/ Tryptophan	47.64 (20.42)	53.06 (28.16)	50.65 (25.08)	48.85 (21.75)	52.59 (22.12)

^a,b,c

significant independent samples t-test (p < .05)