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. Author manuscript; available in PMC: 2010 Nov 1.
Published in final edited form as: Genes Brain Behav. 2009 Jun 26;8(8):744–752. doi: 10.1111/j.1601-183X.2009.00519.x

Figure 4.

Figure 4

Comparison of 129S1 and B6 for fear conditioning, extinction and extinction retrieval using a stronger conditioning protocol. (A) Freezing was significantly higher in 129S1 than B6 on the 3rd, 4th and 5th conditioning trials, on all trials except the 2nd during extinction training, and on all trials during extinction retrieval (*p<.05 vs. B6/same trial(s), #p<.05 vs. extinction trial-block 1 in B6). (B) Temporal analysis of the first extinction trial revealed that freezing was no different between 129S1 and B6 during the first 30-sec timebin, but significantly differed between strains on subsequent timebins (*p<.05 vs. B6/same timebin). Freezing significant increased over timebins in 129S1 and significantly decreased in B6 (#p<.05 vs. timebin 1). n=5–8/strain. Data are Means ± SEM.