Table 1. Demographic and clinical characteristics of solid organ transplant recipients with central nervous system cryptococcosis (n=80).
| Variables | |
|---|---|
| Age, mean (interquartile range), year | 51.5 (43-60) |
| Male, % (n) | 73.8 (59/80) |
| Type of transplant, % (n) | |
| Kidney | 55.0 (44) |
| Liver | 21.2 (17) |
| Lung | 5 (4) |
| Heart | 5 (4) |
| Pancreas | 2.5 (2) |
| Multi-organ | 11.3 (9) |
| Kidney-pancreas | 6.2 (5) |
| Kidney-heart | 2.5 (2) |
| Kidney-liver | 2.5 (2) |
| Primary immunosuppressive agents, % (n) | |
| Tacrolimus | 68.7 (55) |
| Cyclosporine A | 15.0 (12) |
| Others1 | 16.2 (13) |
| Other immunosuppression, % (n) | |
| Prednisone | 96.2 (77) |
| Dose, median (interquartile range), mg/day | 10 (5-10) |
| Mycophenolate mofetil | 53.7 (43) |
| Anti-T cell antibody | 7.5 (6) |
| Renal failure at baseline | 30.0 (24) |
| Retransplantation | 11.2 (9) |
| Rejection | 22.5 (18) |
| Cytomegalovirus infection | 20.0 (16) |
| Cytomegalovirus disease | 8.7 (7) |
1
Others included azothioprine (9), mycophenolate mofetil and prednisone (2), rapamycin, mycophenolate mofetil and prednisone (1), and prednisone only (1)