Table 1.

Characteristics of subjects

Pair	Control subjects							Schizophrenia subjects
	Case	Sex/race	Age	PMI a	RIN	Storage time b	Cause of death c	Case	DSM IV diagnosis	Sex/race	Age	PMI a	RIN	Storage time b	Cause of death c	Antipsychotic medication d
1	592	M/B	41	22.1	9.0	100	ASCVD	533	Chronic undifferentiated schizophrenia	M/W	40	29.1	8.4	110	Accidental asphyxiation	Typical
2	567	F/W	46	15.0	8.9	104	Mitral valve prolapse	537	Schizoaffective disorder	F/W	37	14.5	8.6	109	Suicide by hanging	None
3	516	M/B	20	14.0	8.4	111	Homicide by gun shot	547	Schizoaffective disorder	M/B	27	16.5	7.4	107	Heat stroke	Typical
4	630	M/W	65	21.2	9.0	94	ASCVD	566	Chronic undifferentiated schizophrenia e	M/W	63	18.3	8.0	104	ASCVD	Atypical
5	604	M/W	39	19.3	8.6	97	Hypoplastic coronary artery	581	Chronic paranoid schizophreniaf,g	M/W	46	28.1	7.9	102	Accidental combined drug overdose	Typical
6	546	F/W	37	23.5	8.6	108	ASCVD	587	Chronic undifferentiated schizophreniae	F/B	38	17.8	9.0	101	Myocardial hypertrophy	Both
7	551	M/W	61	16.4	8.3	107	Cardiac tamponade	625	Chronic disorganized schizophrenia h	M/B	49	23.5	7.6	95	ASCVD	Typical
8	685	M/W	56	14.5	8.1	87	Hypoplastic coronary artery	622	Chronic undifferentiated schizophrenia	M/W	58	18.9	7.4	95	Right MCA infarction	None
9	681	M/W	51	11.6	8.9	87	Hypertrophic cardiomyopathy	640	Chronic paranoid schizophrenia	M/W	49	5.2	8.4	93	Pulmonary embolism	Atypical
10	806	M/W	57	24.0	7.8	66	Pulmonary thromboembolism	665	Chronic paranoid schizophrenia f	M/B	59	28.1	9.2	90	Intestinal hemorrhage	Typical
11	822	M/B	28	25.3	8.5	63	ASCVD	787	Schizoaffective disorder i	M/B	27	19.2	8.4	70	Suicide by gun shot	Typical
12	727	M/B	19	7.0	9.2	80	Trauma	829	Schizoaffective disorderf,j	M/W	25	5.0	9.3	61	Suicide by drug overdose	None
13	871	M/W	28	16.5	8.5	53	Trauma	878	Disorganized schizophrenia f	M/W	33	10.8	8.9	52	Myocardial fibrosis	Atypical
14	575	F/B	55	11.3	9.6	102	ASCVD	517	Chronic disorganized schizophrenia f	F/W	48	3.7	9.3	111	Intracerebral hemorrhage	Atypical
15	700	M/W	42	26.1	8.7	84	ASCVD	539	Schizoaffective disorder k	M/W	50	40.5	8.1	109	Suicide by combined drug overdose	Atypical
16	988	M/W	82	22.5	8.4	31	Trauma	621	Chronic undifferentiated schizophrenia	M/W	83	16.0	8.7	95	Accidental asphyxiation	None
17	686	F/W	52	22.6	8.5	87	ASCVD	656	Schizoaffective disorder f	F/B	47	20.1	9.2	91	Suicide by gun shot	Atypical
18	634	M/W	52	16.2	8.5	93	ASCVD	722	Undifferentiated schizophreniaj,l	M/B	45	9.1	9.2	81	Upper GI bleeding	Typical
19	852	M/W	54	8.0	9.1	56	Cardiac tamponade	781	Schizoaffective disorder k	M/B	52	8.0	7.7	71	Peritonitis	Typical
20	987 m	F/W	65	21.5	9.1	31	ASCVD	802	Schizoaffective disorderf,l	F/W	63	29.0	9.2	67	Right ventricular dysplasia	Both
21	818	F/W	67	24.0	8.4	64	Anaphylactic reaction	917	Chronic undifferentiated schizophrenia	F/W	71	23.8	7.0	44	ASCVD	Typical
22	857	M/W	48	16.6	8.9	55	ASCVD	930	Disorganized schizophreniaj,k	M/W	47	15.3	8.2	41	ASCVD	Typical
23	739	M/W	40	15.8	8.4	79	ASCVD	933	Disorganized schizophrenia	M/W	44	8.3	8.1	40	Myocarditis	Atypical
Mean			48.0	18.0	8.7	80.0					47.9	17.8	8.4	84.3
SD			15.5	5.5	0.4	23.6					14.1	9.3	0.7	23.7

^aPMI indicates postmortem interval in hours.

^bStorage time (months) at −80°C.

^cASCVD indicates arteriosclerotic cardiovascular disease.

^dIndicates prescribed antipsychotic medications at time of death.

^eAlcohol abuse, in remission at time of death.

^fAlcohol dependence, current at time of death.

^gOther substance abuse, current at time of death.

^hAlcohol abuse, current at time of death.

ⁱOther substance dependence, current at time of death.

^jOther substance abuse, in remission at time of death.

^kAlcohol dependence, in remission at time of death.

^lOther substance dependence, in remission at time of death.

^mHistory of post-traumatic stress disorder, in remission 39 years at time of death.