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. Author manuscript; available in PMC: 2010 Nov 15.
Published in final edited form as: Biol Psychiatry. 2009 Jul 17;66(10):911–917. doi: 10.1016/j.biopsych.2009.05.027

Figure 1.

Figure 1

ENGRAILED 2 LD map. Inter-marker r2 values for rs1861973 are shown. The map includes 26 EN2 polymorphisms typed in the AGRE I dataset (167 families not subset on ethnicity) plus 3120 Hapmap SNPs within 2Mb of EN2 (+1Mb 5', -1Mb 3') typed in the CEU dataset. Only rs1861972 and rs2361688 display high r2 values (>.75) with rs1861973. However, rs2361688 is not consistently associated with ASD 15, identifying rs1861972 and rs1861973 as the most appropriate candidates to test for functional allelic differences.