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. Author manuscript; available in PMC: 2010 Nov 1.
Published in final edited form as: J Autoimmun. 2009 Oct 9;33(3-4):197–207. doi: 10.1016/j.jaut.2009.09.008

Table 1.

Recent Prevalence Data for Autoimmune Diseases, by Geographic Area

Hospital-based Data, Denmarkb Hospital and non-Hospital- based Data
Studies from Europe, North America, Australia, New Zealand Studies from Asia, Middle East, Caribbean, South America


Diseasea Rate per 100,000 Rate per 100,000 Study Area Reference Rate per 100,000 Study Area Reference
Addison 18 11–14 UK, Italy, Norway [46]
Alopecia 21 1700 US [7]
Celiac disease 50 180–350 Greece, Netherlands [8,9] 140–280 Iran, Tunisia [1315]
740–1000 Iceland, Italy [10,11] 470–600 Brazil, Argentina [16, 17]
1900 Finland [12] 900 Turkey [18]
Crohn disease 225 28–53 Bosnia-Herzegovina, Hungary [19,20] 6–53 Puerto Rico, Malaysia, Lebanon [2729]
96–201 US, Spain, Denmark, New Zealand [2126] 113 Israel [30]
Ulcerative colitis 378 143–294 US, Hungary, Denmark, New Zealand [19,2123,25, 26] 6 Lebanon [29]
102 Puerto Rico [27]
Diabetes
 All ages 946 118 Lithuania [31]
 All ages 340–570 UK, Sweden, Australia [3234]
 Ages < 20 87–120 Spain, Germany [35, 36] 31 Bahamas [40]
 Ages < 20 227–355 US, New Zealand [37, 38] 110–270 Kuwait, Saudi Arabia [41,42]
 Ages < 20 70 US- American Indian [39]
Liver - Chronic active hepatitis 45 11–17 Spain, Sweden, Norway [4345] 3–8 Singapore [47]
36 US-Alaska Natives [46]
Liver - Primary biliary cirrhosis 12 15–40 Norway, Finland, Spain, UK, [45,4851] 4–18 Israel [53]
4–20 US Australia [52]
Thyroid - Hyper 629 500 US [54] 20 Iran [56]
626 UK [55]
Thyroid - Hypo 62 300 US [54] 350 Iran [56]
2980 UK [55]
Multiple sclerosis 182 177–358 US, Canada [5760] 4–20 Colombia, Brazil, Argentina [7274]
100 Canada-First Nations [60] 13 Japan [75]
121–200 Italy, Greece, France, Ireland, [6169] 11–62 Israel, Kuwait, Jordan, Iran [7679]
46 Norway [70] 101 Turkey [80]
50 Portugal New Zealand [71]
Myasthenia gravis 18 8–15 Greece, Estonia, Croatia [8183] 3 Colombia [87, 88]
Netherlands, Sweden, UK [8486] 7 Curacuo and Aruba
Polymyalgia rheumatica 112 739b US [89, 90]
150–370b Greece [91]
Psoriasis 197 696–1527 US, UK [92, 93]
Psoriatic arthritis 57 Greece [94]
140–190 Iceland, Norway, Denmark, US [9598]
500 Australia-Aboriginie [99]
Rheumatoid arthritis 381 310–810 France, Hungary, Spain, Turkey, Greece, UK [91,100105] 120–280 Thailand, Phillipines, Vietnam, China [106109]
510–550 India, Pakistan, Argentina [110]
197 [111]
Sjögren disease 48 3500 UK [112] 330–770 China [118]
110 Denmark (ages 30–60) [113] 720–1560 Turkey (women) [119]
93–150 Greece [91,114,115]
600 Greece - (women) [116]
600 Slovenia [117]
Systemic sclerosis 23 5–34 France, Greece, Spain, Italy, US [120125] 20–24 Australia [127]
10–66 US-Native Americans [126] 30 Phillipines [107]
Systemic lupus erythematosus 32 34–150 US, Spain, Greece [128131] 19 Saudi Arabia [133]
42 Canada-1st Nations [132] 45 Australia [134]
93 Australia-aboriginal [134]
Systemic vasculitis 9–14 France, UK [135, 136] 10 Australia [137]
Wegener granulo-matosis 10 2–10 France, Norway, Australia, New Zealand [135, 137140]
Uveitis (iridocycltis) 149 69–115 US, Finland [141143] 730 India [144]
Vitiligo 29 93 China [145]
a

Addison = primary adrenal insufficiency; diabetes = type 1 diabetes, systemic vasculitis based on the total of polyarteritis nodosa, microscopic polyangiitis, Wegener's granulomatosis, and Churg-Strauss syndrome.

b

based on data from Eaton et al., 2007; population-based study in Denmark using hospitalization records from 2001

c

rates per population ages >= 50 years