Appendix I Table 1.
Characteristics of Patients with deletion 5q Who Presented with Lower Risk MDS
| No. (%) | |||
|---|---|---|---|
| Parameter | Category | IPSS Low- Intermediate 1 (n=93) |
Less Than 5 % Blasts (n=115) |
| Age (years) | ≥ 60 | 74 (80) | 85 (74) |
| Gender | Female | 47 (51) | 53 (46) |
| Hemoglobin (g/dl) | < 10 | 65 (70) | 92 (80) |
| Platelets (×109/L) | < 100 | 16 (17) | 53 (46) |
| WBC (×109/L) | < 1 | 0 | 1 (1) |
| Absolute granulocyte count (×109/L) | < 1 | 7 (8) | 24 (21) |
| Marrow blasts % | < 5 | 73 (79) | 115 (100) |
| 5–10 | 18 (19) | 0 | |
| 10–19 | 2 (2) | 0 | |
| FAB morphology | RA-RAS | 67 (72) | 98 (85) |
| RAEB | 25 (27) | 14 (12) | |
| RAEBT | 1 (1) | 1 (1) | |
| CMML | 0 | 2 (2) | |
| IPSS risk | Low | 27 (29) | 27 (24) |
| Intermediate 1 | 66 (71) | 46 (40) | |
| Prior therapy | No | 41 (44) | 65 (57) |
| Yes | 52 (56) | 50 (44) | |
| Duration of MDS (mos) | < 3 | 16 917) | 34 (30) |
| 3–12 | 35 (37) | 43 (37) | |
| > 12 | 42 (45) | 38 (33) | |
| Cytogenetic abnormalities in addition | + 1 | 19 (20) | 15 (13) |
| to chromosome 5 | + 2 | 7 (8) | 11 (10) |
| + ≥ 3 | 6 (7) | 21 (18) | |
| + chromosome 7 abnormality |
6 (7) | 27 (23) | |