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. Author manuscript; available in PMC: 2010 Nov 30.
Published in final edited form as: Respir Physiol Neurobiol. 2009 Aug 3;169(2):141–149. doi: 10.1016/j.resp.2009.07.021

Figure 4. Induction of uPA mRNA in the PMN following C2-hemisection.

Figure 4

In situ hybridization of uPA mRNA using a 35S-cRNA probe in the C4 mouse spinal cord 1h following a left C2HS (B) compared to an uninjured mouse (A). Induced uPA mRNA expression is restricted to the ventral spinal cord in a limited number of large motorneurons in the ipsilateral PMN. The PMN induction is specific with no uPA mRNA expression in the contralateral spinal cord, or above the PMN at the C2-C3 interface (C), or below the PMN at the C6-C7 interface (D). The magnification bar in A is 250µm and the same for all four panels, while the bar in B inset is 50µm.