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. Author manuscript; available in PMC: 2010 Nov 10.
Published in final edited form as: Circulation. 2009 Oct 26;120(19):1893–1902. doi: 10.1161/CIRCULATIONAHA.109.866889

Figure 1. Plasma levels of Hcy and Met, and organ weight in transgenic CBS deficient mice.

Figure 1

Tg-hCBSapoE−/− Cbs mice were fed a HF diet at 8 weeks of age for an additional 8 weeks. The Tg-S466L Cbs and Tg-hCBS apoE−/−Cbs mice were fed a rodent chow. A, B & C, Plasma levels of Hcy and Met. D, Body weight, E, F, G and H. heart, liver, spleen and kidney weights relative to tibia lengths, respectively. Values are mean±SD. P values from independent t test. n=10–12, Hcy, homocysteine; Met, methionine, HF, high fat.