. Author manuscript; available in PMC: 2010 Sep 1.

Published in final edited form as: Synapse. 2009 Sep;63(9):717–728. doi: 10.1002/syn.20652

TABLE III.

Absolute D₂ and D₃ receptor densities density ratios in rhesus monkey caudate, putamen and rat striatum

	B₁ fmol/mg Tissue	B₂ fmol/mg Tissue	D₂ fmol/mg Tissue	D₃ fmol/mg Tissue	D₂:D₃
Rhesus caudate	125 ± 3	318 ± 17	310 ± 21	141 ± 2	2.20 ± 0.16
Rhesus putamen	141 ± 4	345 ± 23	307 ± 30	130 ± 5	2.36 ± 0.2
Rat striatum	38 ± 2	145 ± 4	143 ± 7	68 ± 3	2.11 ± 0.23

Apparent binding densities (B₁ and B₂) of 4 nM [³H]WC-10 and 10 nM [³H]raclopride were directly measured with quantitative autoradiography; absolute D₂ and D₃ receptor densities and the receptor density ratios D₂:D₃ were calculated from the equations (5) and (6) using the a₁, b₁, a₂, and b₂ values in the Table II and the B₁, B₂ values in this Table. Data were presented as mean value ± S.E.M, n=8 for rhesus monkey caudate-putamen and n=30 for rat striatum.