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. Author manuscript; available in PMC: 2010 Nov 1.
Published in final edited form as: Cancer Res. 2009 Oct 6;69(21):8349–8355. doi: 10.1158/0008-5472.CAN-09-1669

Table 5.

Relative risks (RR) of glioma in relation to physical activity level at specific ages.

Variable MET-h of physical activity per week P for
trend
≤11.5 11.6-26.5 26.6-41.5 41.6-51.5 51.6+
Activity between age 15-18 y
 No. of cases 50 53 40 50 64
 Age and sex adjusted RR 1.00 0.96 0.91 0.92 0.67 0.03
 95% CI ref 0.65, 1.41 0.60, 1.38 0.62, 1.36 0.46, 0.97
 Multivariate1 RR 1.00 0.93 0.85 0.87 0.64 0.02
 95% CI ref 0.63, 1.37 0.56, 1.30 0.59, 1.29 0.44, 0.93
 Mutually adjusted2 RR 1.00 0.93 0.87 0.87 0.64 0.02
 95% CI ref 0.63, 1.37 0.57, 1.33 0.58, 1.30 0.43, 0.94
Activity between age 19-29 y
 No. of cases 53 51 30 65 58
 Age and sex adjusted RR 1.00 0.71 0.73 0.94 0.67 0.21
 95% CI ref 0.49, 1.05 0.47, 1.15 0.66, 1.36 0.46, 0.97
 Multivariate RR 1.00 0.69 0.70 0.91 0.65 0.17
 95% CI ref 0.47, 1.02 0.45, 1.10 0.63, 1.31 0.44, 0.94
 Mutually adjusted3 RR 1.00 0.73 0.77 1.12 0.94 0.58
 95% CI ref 0.48, 1.11 0.46, 1.27 0.71, 1.77 0.56, 1.57
Activity between age 35-39 y
 No. of cases 53 64 27 62 51
 Age and sex adjusted RR 1.00 0.85 0.79 0.97 0.79 0.45
 95% CI ref 0.59, 1.23 0.50, 1.26 0.67, 1.40 0.53, 1.16
 Multivariate RR 1.00 0.83 0.77 0.94 0.78 0.42
 95% CI ref 0.58, 1.20 0.48, 1.22 0.65, 1.36 0.53, 1.15
 Mutually adjusted3 RR 1.00 0.90 0.85 1.14 1.05 0.49
 95% CI ref 0.62, 1.31 0.52, 1.38 0.76, 1.71 0.67, 1.66
Activity during the past 10 y
 No. of cases 51 77 26 55 48
 Age and sex adjusted RR 1.00 1.03 0.83 0.95 0.89 0.43
 95% CI ref 0.72, 1.47 0.52, 1.33 0.65, 1.39 0.60, 1.32
 Multivariate RR 1.00 0.99 0.78 0.91 0.86 0.36
 95% CI ref 0.69, 1.41 0.49, 1.26 0.62, 1.33 0.58, 1.28
 Mutually adjusted3 RR 1.00 1.04 0.83 1.01 1.01 0.90
 95% CI ref 0.73, 1.49 0.51, 1.34 0.68, 1.50 0.66, 1.53
1

Multivariate models are adjusted for age at baseline, age-squared, gender, race (White, Black, other), highest level of education (did not complete high school, completed high school, some college, completed college), and marital status (married, divorced, separated, widowed, unmarried). Models of physical activity between 15-18 y were additionally adjusted for height at age 18 (<1.60, 1.60-1.64, 1.65-1.69, 1.70-1.74, 1.75-1.79, 1.80-1.84, 1.85-1.90, 1.90+), and BMI at age 18 (<18.5, 18.5-24.9, 25.0-29.9, 30.0-34.9, 35.0+ kg/m2). Models of physical activity between 19-29 y were adjusted for BMI at age 18 and adult height. Models of physical activity between 35-39 y were adjusted for BMI at age 35 and adult height. Models of physical activity during the past 10 y were adjusted for baseline BMI and adult height.

2

Additionally adjusted for physical activity during the past 10 y.

3

Additionally adjusted for physical activity during the ages 15-18 y.