TABLE 3.

Genotypes, viral load, and amino acid substitutions in the VP1 region of BKV isolates from urine of PVAN patients.

			Amino acid substitution a
Patient	Genotype	Viral load b	BC loop	DE loop	EF loop
1	I	6,06E+07	K69R	-	D175E V210I
2	I	6,26E+08	E82D	H139N	D175E V210I
3	I	7,20E+08	D75N E82D	H139N	D175E V210I
4	IV	1,78E+06	D77E	-	-
5	IV	6,30E+08	-	-	-
6	IV	N/A c	D77E E73Q	-	-
7	I	7,93E+09	-	-	D175E V210I
8	IV	1,25E+06	-	-	-

^aamino acid numbers are those of Dunlop strain (Seif et al., 1979);

^bcopies/ml;

^cN/A= not available;

amino acid substitutions that cause a change of charge are underscored.